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Effects of deferoxamine on the levels of matrix metalloproteinase-3 and the blood-brain barrier after cerebral ischemia reperfusion in rats  期刊论文  

  • 编号:
    02b72dc9-6bfc-4150-8d66-4a16150597b0
  • 作者:
    Meng, Meng;Wu, Jiang (1, 2);Yang, Yi (1, 2)(杨弋);Zhang, Jie (1, 2);Xing, Yingqi(邢英琦)
  • 作者单位:
    (1) Department of Neurology, China Aerospace and Science Industry Corporation 731 Hospital, Beijing, China (2) Department of Neurology, The First Hospital of Jilin University, Jilin, China
  • 语种:
    英文
  • 会议名称:
    WIT Transactions on Biomedicine and Health
  • 会议地点:
    Wuhan, China
  • 收录:
  • 摘要:

    Hemorrhagic transformation (HT) is a feared complication of recanalization for acute ischemic stroke, and there is no effective solution. Studies have suggested that the iron chelator, Deferoxamine (DFX), can attenuate HT in a rat model of HT. We established a HT rat model by middle cerebral artery occlusion with reperfusion. In HT rats, DFX reduced the extent of brain damage, protected the blood-brain barrier, and reduced the levels of expression of matrix metalloproteinase-3. © 2014 WIT Press.

  • 推荐引用方式
    GB/T 7714:
    Meng Meng (1),Wu Jiang (1 2),Yang Yi (1 2), et al. Effects of deferoxamine on the levels of matrix metalloproteinase-3 and the blood-brain barrier after cerebral ischemia reperfusion in rats [J].WIT Transactions on Biomedicine and Health,2014,18:737-744.
  • APA:
    Meng Meng (1),Wu Jiang (1 2),Yang Yi (1 2),Zhang Jie (1 2),&Xing Yingqi (2).(2014).Effects of deferoxamine on the levels of matrix metalloproteinase-3 and the blood-brain barrier after cerebral ischemia reperfusion in rats .WIT Transactions on Biomedicine and Health,18:737-744.
  • MLA:
    Meng Meng (1), et al. "Effects of deferoxamine on the levels of matrix metalloproteinase-3 and the blood-brain barrier after cerebral ischemia reperfusion in rats" .WIT Transactions on Biomedicine and Health 18(2014):737-744.
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