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A tablet-interfaced high-resolution microendoscope with automated image interpretation for real-time evaluation of esophageal squamous cell neoplasia 期刊论文

编号：

2424cb51-2007-410c-bd3a-3845fef86e1b
作者：

Quang, Timothy#*^[1]Schwarz, Richard A.^[1];Dawsey, Sanford M.^[2];Tan, Mimi C.^[3];Patel, Kalpesh^[3];Yu, Xinying^[4];Wang, Guiqi^[4];Zhang, Fan(张帆)^[5]Xu, Hong(徐红)^[5]Anandasabapathy, Sharmila^[3];RichardsKortum, Rebecca^[1];
语种：

英文
期刊：

GASTROINTESTINAL ENDOSCOPY ISSN：0016-5107 2016 年 84 卷 5 期 (834 - 841) ; NOV
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摘要：

Background and Aims: In recent years high-resolution microendoscopy (HRME) has shown potential to improve screening for esophageal squamous cell neoplasia. Furthering its utility in a clinical setting, especially in lower-resource settings, could be accomplished by reducing the size and cost of the system as well as incorporating the ability of real-time, objective feedback. This article describes a tablet-interfaced HRME with fully automated, real-time image analysis.
Methods: The performance of the tablet-interfaced HRME was assessed by acquiring images from the oral mucosa in a normal volunteer. An automated, real-time analysis algorithm was developed and evaluated using training, test, and validation images from a previous in vivo study of 177 patients referred for screening or surveillance endoscopy in China. The algorithm was then implemented in a tablet HRME that was used to obtain and analyze images from esophageal tissue in 3 patients. Images were displayed alongside the probability that the imaged region was neoplastic.
Results: The tablet-interfaced HRME demonstrated comparable imaging performance at a lower cost compared with first-generation laptop-interfaced HRME systems. In a post-hoc quantitative analysis, the algorithm identified neoplasia with a sensitivity and specificity of 95% and 91%, respectively, in the validation set compared with 84% and 95% achieved in the original study.
Conclusions: The tablet-based HRME is a low-cost tool that provides quantitative diagnostic information to the endoscopist in real time. This could be especially beneficial in lower-resource settings for operators with less experience interpreting HRME images.
推荐引用方式
GB/T 7714：

Quang Timothy,Schwarz Richard A.,Dawsey Sanford M., et al. A tablet-interfaced high-resolution microendoscope with automated image interpretation for real-time evaluation of esophageal squamous cell neoplasia [J].GASTROINTESTINAL ENDOSCOPY,2016,84(5):834-841.
APA：

Quang Timothy,Schwarz Richard A.,Dawsey Sanford M.,Tan Mimi C.,&Richards-Kortum Rebecca.(2016).A tablet-interfaced high-resolution microendoscope with automated image interpretation for real-time evaluation of esophageal squamous cell neoplasia .GASTROINTESTINAL ENDOSCOPY,84(5):834-841.
MLA：

Quang Timothy, et al. "A tablet-interfaced high-resolution microendoscope with automated image interpretation for real-time evaluation of esophageal squamous cell neoplasia" .GASTROINTESTINAL ENDOSCOPY 84,5(2016):834-841.
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