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A combined biomarker pattern improves the discrimination of lung cancer 期刊论文

编号：

24c68ecc-02fc-484d-9414-6eb8efd64475
作者：

Liu, Liyun#^[1,2,3]Liu, Jifu^[4];Wang, Yinping^[5];Dai, Songwei^[1,2];Wang, Xiaomin^[1,2];Wu, Shanshan^[4];Wang, Jianing^[1,2];Huang, Lingyun^[1,2];Xiao, Xueyuan(肖雪媛)*^[1,2]He, Dacheng(何大澄)*^[1,2]
语种：

英文
期刊：

BIOMARKERS ISSN：1354-750X 2011 年 16 卷 1 期 (20 - 30) ; FEB
收录：
关键词：

SELDI lung cancer biomarker TTR SAA
摘要：

A total of 227 sera were analysed using surface-enhanced laser desorption/ ionization time-of-flight mass spectrometry (SELDI-TOF MS) to find novel serum biomarkers for lung cancer. The results showed that the 11.53, 11.70, 13.78, 13.90 and 14.07 k m/z peaks identified as native serum amyloid A (SAA), SAA with N-terminal Arg cleaved, native transthyretin (TTR) and its two variants significantly differentiated lung cancer sera from normal control sera (p <0.01). A "biomarker pattern" combining SAA and TTR was tested to distinguish lung cancer patients from normal control individuals, and the diagnostic positive rate of lung cancer was improved to 91.6%.
推荐引用方式
GB/T 7714：

Liu Liyun,Liu Jifu,Wang Yinping, et al. A combined biomarker pattern improves the discrimination of lung cancer [J].BIOMARKERS,2011,16(1):20-30.
APA：

Liu Liyun,Liu Jifu,Wang Yinping,Dai Songwei,&He Dacheng.(2011).A combined biomarker pattern improves the discrimination of lung cancer .BIOMARKERS,16(1):20-30.
MLA：

Liu Liyun, et al. "A combined biomarker pattern improves the discrimination of lung cancer" .BIOMARKERS 16,1(2011):20-30.
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