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Is Dynamic Cerebral Autoregulation Bilaterally Impaired after Unilateral Acute Ischemic Stroke? 期刊论文

编号：

28ad65e6-ef72-492b-9f8a-ab4ba85cdaec
作者：

Xiong, Li#^[1]Tian, Ge#^[1]Lin, Wenhua^[1];Wang, Wei^[2];Wang, Lijuan(王丽娟)^[3]Leung, Thomas^[1];Mok, Vincent^[1];Liu, Jia(刘嘉)*^[4]Chen, Xiangyan(陈向燕)*^[1]Wong, Ka Sing^[1];
语种：

英文
期刊：

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES ISSN：1052-3057 2017 年 26 卷 5 期 (1081 - 1087) ; MAY
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关键词：

Cerebral autoregulation cerebral blood flow blood pressure acute ischemic stroke
摘要：

Objective: Whether dynamic cerebral autoregulation (dCA) is impaired focally in the affected hemisphere or bilaterally in both the affected and nonaffected hemispheres after ischemic stroke remains controversial. We therefore investigated the pattern of dCA in acute ischemic stroke patients with different subtypes. Methods: Sixty acute ischemic stroke patients with unilateral anterior circulation infarct [30 with large artery atherosclerosis (LAA), 13 with small vessel disease (SVD), and 17 with coexisting LAA and SVD] and 16 healthy controls were enrolled. Spontaneous arterial blood pressure and cerebral blood flow velocity fluctuations in both bilateral middle cerebral arteries using transcranial Doppler were recorded over 10 minutes. Transfer function analysis was applied to obtain autoregulatory parameters, autoregulation index (ARI), phase difference (PD), and gain. Results: PD was significantly lower on both the ipsilateral and contralateral sides in the LAA group (ipsilateral, 30.74 degrees; contralateral, 29.17 degrees) and the coexisting LAA and SVD group (20.23 degrees; 13.10 degrees) than that in healthy controls (left side, 51.66 degrees; right side, 58.48 degrees) (all P <.05), but there were no significant differences between the 2 sides when compared with each other in all groups. However, in the coexisting LAA and SVD group, phase on both sides was significantly lower when compared with that in the LAA and SVD groups, respectively. The results of ARI were consistent with the findings in PD. Conclusions: The results indicate that dCA is bilaterally impaired in acute ischemic patients with LAA, and the coexisting SVD may aggravate the bilateral impairment of dCA.
推荐引用方式
GB/T 7714：

Xiong Li,Tian Ge,Lin Wenhua, et al. Is Dynamic Cerebral Autoregulation Bilaterally Impaired after Unilateral Acute Ischemic Stroke? [J].JOURNAL OF STROKE & CEREBROVASCULAR DISEASES,2017,26(5):1081-1087.
APA：

Xiong Li,Tian Ge,Lin Wenhua,Wang Wei,&Wong Ka Sing.(2017).Is Dynamic Cerebral Autoregulation Bilaterally Impaired after Unilateral Acute Ischemic Stroke? .JOURNAL OF STROKE & CEREBROVASCULAR DISEASES,26(5):1081-1087.
MLA：

Xiong Li, et al. "Is Dynamic Cerebral Autoregulation Bilaterally Impaired after Unilateral Acute Ischemic Stroke?" .JOURNAL OF STROKE & CEREBROVASCULAR DISEASES 26,5(2017):1081-1087.
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