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Antioxidation of Cerium Oxide Nanoparticles to Several Series of Oxidative Damage Related to Type II Diabetes Mellitus In Vitro 期刊论文

编号：

4de7b7e8-72ea-40cf-9652-20dca77640da
作者：

Zhai, Jinghui#^[1,2]Wu, Yi(武毅)^[1]Wang, Xiaoying^[3];Cao, Yue^[2];Xu, Kan(许侃)^[4]Xu, Li(徐力)^[2]Guo, Yi(郭轶)*^[2]
语种：

英文
期刊：

MEDICAL SCIENCE MONITOR ISSN：1643-3750 2016 年 22 卷 (3792 - 3797) ; OCT 18
收录：
关键词：

Diabetes Mellitus, Type 2 Hydrogen Peroxide Islet Amyloid Polypeptide
摘要：

Background: It is well known that cerium oxide nanoparticles (CeNPs) have intense antioxidant activity. The antioxidant property of CeNPs are widely used in different areas of research, but little is known about the oxidative damage of Cu2+ associated with Type II diabetes mellitus (T2DM).
Material/Methods: In our research, the function of CeNPs was tested for its protection of beta-cells from the damage of Cu2+ or H2O2. We detected hydroxyl radicals using terephthalic acid assay, hydrogen peroxide using Amplex Ultra Red assay, and cell viability using MTT reduction.
Results: We found that CeNPs can persistently inhibit Cu2+/H2O2 evoked hydroxyl radicals and hydrogen peroxide in oxidative stress of beta-cells.
Conclusions: CeNPs will be useful in developing strategies for the prevention of T2DM.
推荐引用方式
GB/T 7714：

Zhai Jing-hui,Wu Yi,Wang Xiao-ying, et al. Antioxidation of Cerium Oxide Nanoparticles to Several Series of Oxidative Damage Related to Type II Diabetes Mellitus In Vitro [J].MEDICAL SCIENCE MONITOR,2016,22:3792-3797.
APA：

Zhai Jing-hui,Wu Yi,Wang Xiao-ying,Cao Yue,&Guo Yi.(2016).Antioxidation of Cerium Oxide Nanoparticles to Several Series of Oxidative Damage Related to Type II Diabetes Mellitus In Vitro .MEDICAL SCIENCE MONITOR,22:3792-3797.
MLA：

Zhai Jing-hui, et al. "Antioxidation of Cerium Oxide Nanoparticles to Several Series of Oxidative Damage Related to Type II Diabetes Mellitus In Vitro" .MEDICAL SCIENCE MONITOR 22(2016):3792-3797.
入库时间：

12/16/2019 3:17:30 PM
更新时间：

12/16/2019 3:17:30 PM
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