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Interaction Between Scutellaria baicalensis Georgi and Human Serum Albumin 期刊论文

编号：

6dbdf566-3f91-4bc3-b06d-d23ca05cc4f7
作者：

Wang Ning#^[2,3]Liu ZhongYing^[3];Hu XiuLi^[3];Bu FengQuan^[3];Zhao XueZhong(赵学忠)*^[1]
语种：

中文
期刊：

CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE ISSN：0251-0790 2011 年 32 卷 2 期 (241 - 245) ; FEB 10
收录：
关键词：

Baicalin Wogonoside Human serum albumin Fluorescence quenching
摘要：

The interactions of baicalin and wogonoside with human serum albumin (HSA) were studied by fluorescence quenching and ultraviolet-visible absorption spectrometry. The binding constants were obtained by fluorescence quenching of drug with serum albumin. The main acting binding forces of baicalin and wogonoside to serum albumins were hydrophobic force according to the thermodynamic parameters. The effects of metal ions, such as Zn2+, Mg2+, Al3+ and Cu2+ on binding constants were also evaluated. It is not only valuable to reveal the pharmacokinetics, clinical therapy, but also guiding significance for drug design and development of new drugs.
推荐引用方式
GB/T 7714：

Wang Ning,Liu Zhong-Ying,Hu Xiu-Li, 等. Interaction Between Scutellaria baicalensis Georgi and Human Serum Albumin [J].CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2011,32(2):241-245.
APA：

Wang Ning,Liu Zhong-Ying,Hu Xiu-Li,Bu Feng-Quan,&Zhao Xue-Zhong.(2011).Interaction Between Scutellaria baicalensis Georgi and Human Serum Albumin .CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,32(2):241-245.
MLA：

Wang Ning, et al. "Interaction Between Scutellaria baicalensis Georgi and Human Serum Albumin" .CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 32,2(2011):241-245.

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