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Seroprevalence and Risk Factors for Hepatitis B Infection in an Adult Population in Northeast China 期刊论文

编号：

85ff0325-17b0-4d88-8805-38cff5f80390
作者：

Zhang, Hong(张洪)#^[1]Li, Qingmei(李青梅)#^[1]Sun, Jie(孙捷)^[1]Wang, Chunyan(王春艳)^[1]Gu, Qing^[1];Feng, Xiangwei(冯相伟)^[1]Du, Bing^[1];Wang, Wei^[1];Shi, Xiaodong^[1];Zhang, Siqi^[1];Li, Wanyu^[1];Jiang, Yanfang(姜艳芳)^[1]Feng, Junyan^[1];He, Shumei(何淑梅)*^[1]Niu, Junqi(牛俊奇)*^[1]
语种：

English
期刊：

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES ISSN：1449-1907 2011 年 8 卷 4 期 (321 - 331)
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关键词：

hepatitis B immunity seroepidemiologic study vaccine
摘要：

Background and aim: The prevalence of the hepatitis B virus (HBV) is higher in adults than in children. We determined the seroepidemiology of HBV infection in an adult population in JiLin, China, to guide effective preventive measures. Methods: A cross-sectional serosurvey was conducted throughout JiLin, China. A total of 3833 people was selected and demographic and behavioral information gathered. Serum samples were tested for HBV markers and liver enzymes. Results: The prevalence of the hepatitis B surface antigen (HBsAg), the antibody to the hepatitis B surface antigen (anti-HBs), the hepatitis B e antigen (HBeAg), the antibody to HBeAg (anti-HBe), and the antibody to the hepatitis B core antigen (anti-HBc) were 4.38%, 35.66%, 1.38%, 6.65%, and 40.88%, respectively. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels were significantly higher among HBsAg (+) than HBsAg (-) subjects. By multivariate logistic regression analysis, independent predictors for chronic HBV infection were smoking, poor sleep quality; occupation as private small-businessmen, laborers, or peasants; male gender; family history of HBV; personal history of vaccination; and older age. Independent predictors for exposure to HBV were large family size, occupation as a private small-businessman, male gender, family history of HBV, personal history of vaccination, and older age. Independent predictors for immunity by vaccination were occupation as a private small-businessman, high income, personal history of vaccination, and young age. Independent predictors for immunity by exposure were drinking, male gender, personal history of vaccination, and older age. Conclusions: The prevalence rate of HBV infection (4.38%) was lower than the previous rate of general HBV vaccination. However, 44.59% of the population remained susceptible to HBV. The prevalence of HBV infection was high in young adults, private small-businessmen, peasants, those with a family history of HBV, and males. Therefore, immunization of the non-immune population is reasonable to reduce hepatitis B transmission between adults.
推荐引用方式
GB/T 7714：

Zhang Hong,Li Qingmei,Sun Jie, et al. Seroprevalence and Risk Factors for Hepatitis B Infection in an Adult Population in Northeast China [J].INTERNATIONAL JOURNAL OF MEDICAL SCIENCES,2011,8(4):321-331.
APA：

Zhang Hong,Li Qingmei,Sun Jie,Wang Chunyan,&Niu Junqi.(2011).Seroprevalence and Risk Factors for Hepatitis B Infection in an Adult Population in Northeast China .INTERNATIONAL JOURNAL OF MEDICAL SCIENCES,8(4):321-331.
MLA：

Zhang Hong, et al. "Seroprevalence and Risk Factors for Hepatitis B Infection in an Adult Population in Northeast China" .INTERNATIONAL JOURNAL OF MEDICAL SCIENCES 8,4(2011):321-331.
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