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Biomimetic Glycopolymer Tethered Gold Nanorods for Remote NIR Triggered Drug Release  期刊论文  

  • 编号:
    94ee2ca1-fd77-4ca7-8b40-e96e2e274e7e
  • 作者:
  • 语种:
    中文
  • 期刊:
    ACTA POLYMERICA SINICA ISSN:1000-3304 2015 年 10 期 (1128 - 1132) ; OCT 20
  • 收录:
  • 关键词:
  • 摘要:

    Biomimetic thiol terminated glycopolymers PGAMA-PCL-SH were effectively anchored on the surface of gold nanorods to prepare the biomimetic glycopolymers modified gold nanoparticles (Gly@ Au NRs). UV-Vis, XPS, DLS and TGA were used to characterize Gly@ Au NRs. NIR-induced heating of an aqueous suspension of Gly@ Au NRs was performed. Then, curcumin (CUR) was loaded into Gly@ Au NRs and the in vitro release of CUR was studied. We found that the NIR-laser irradiation can control the drug release effectively. Moreover, cell viability studies revealed that the cytotoxicity of the Gly@ Au NRs complexes was remarkably improved as compared to that of the original Au NRs. Consequently, the Gly@ Au NRs complexes can be used as biocompatible vehicles to realize the controlled drug release by remote NIR-laser irradiation.

  • 推荐引用方式
    GB/T 7714:
    Song Rong-guang,Li Yan-chun,Shi Tong-fei, 等. Biomimetic Glycopolymer Tethered Gold Nanorods for Remote NIR Triggered Drug Release [J].ACTA POLYMERICA SINICA,2015(10):1128-1132.
  • APA:
    Song Rong-guang,Li Yan-chun,Shi Tong-fei,Pei Dan-feng,&Zhang Guo.(2015).Biomimetic Glycopolymer Tethered Gold Nanorods for Remote NIR Triggered Drug Release .ACTA POLYMERICA SINICA(10):1128-1132.
  • MLA:
    Song Rong-guang, et al. "Biomimetic Glycopolymer Tethered Gold Nanorods for Remote NIR Triggered Drug Release" .ACTA POLYMERICA SINICA,10(2015):1128-1132.
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