首页 / 院系成果 / 成果详情页

Therapeutic effect of recombinant lentiviral vector containing succinate dehydrogenase iron-sulfur protein on the treatment of experimental autoimmunity myocarditis  期刊论文  

  • 编号:
    979c168c-43c0-4006-94e1-ad0d2cd464a4
  • 作者:
  • 语种:
    英文
  • 期刊:
    MEDICAL HYPOTHESES ISSN:0306-9877 2016 年 93 卷 (97 - 101) ; AUG
  • 收录:
  • 摘要:

    Cardiac autoimmune reaction takes part in myocarditis, dilated cardiomyopathy and heart failure. Existing literature has confirmed that the occurrence of cardiomyopathy belongs to mitochondrial diseases and is related to the oxidative respiratory chain subunit. The special structure of iron-sulfur protein (ISP) is responsible for the oxidative stress in oxidative phosphorylation, which is also a target that is easily attacked by various damage factors. Using gene therapy technology to restore succinate dehydrogenase iron-sulfur protein (SDISP) function and thus resume myocardial mitochondria function and myocardial function is hypothesized to alleviate the experimental autoimmunity myocarditis (EAM). (C) 2016 Elsevier Ltd. All rights reserved.

  • 推荐引用方式
    GB/T 7714:
    Han Lina,Wang Chunxi,Guo Shuli, et al. Therapeutic effect of recombinant lentiviral vector containing succinate dehydrogenase iron-sulfur protein on the treatment of experimental autoimmunity myocarditis [J].MEDICAL HYPOTHESES,2016,93:97-101.
  • APA:
    Han Lina,Wang Chunxi,Guo Shuli,Liu Siyu,&Yang Liming.(2016).Therapeutic effect of recombinant lentiviral vector containing succinate dehydrogenase iron-sulfur protein on the treatment of experimental autoimmunity myocarditis .MEDICAL HYPOTHESES,93:97-101.
  • MLA:
    Han Lina, et al. "Therapeutic effect of recombinant lentiviral vector containing succinate dehydrogenase iron-sulfur protein on the treatment of experimental autoimmunity myocarditis" .MEDICAL HYPOTHESES 93(2016):97-101.
  • 条目包含文件:
    文件类型:PDF,文件大小:
    正在加载全文
浏览次数:65 下载次数:0
浏览次数:65
下载次数:0
打印次数:0
浏览器支持: Google Chrome   火狐   360浏览器极速模式(8.0+极速模式) 
返回顶部