[1]Department of Hepatology, First Hospital of Jilin University, Jilin, China.
Background: Portal ductopathy has been widely accepted as a disease that the anatomy morphological and functional abnormalities of intrahepatic and extrahepatic bile duct, cystic gall duct and gallbladder which are leaded by extrahepatic portal vein obstruction. Symptomatic portal ductopathy is unusual. Methods: In our department, 1 case of chronic alcoholic cirrhosis complicated with portal ductopathy developed to chronic liver failure who were treated successfully by internal medicine treatment, artificial liver plasma exchange therapy and liver transplantation. A 41-year old man had 3-years liver cirrhosis related to alcoholic. He developed liver failure after 1 month abdominal distension and edema of lower limbs, then icteric sclera and yellowish urine for 15 days. Laboratory examination showed increased bilirubin and failed blood coagulation function. On CT and pathology, broadening portal vein oppressed the bile duct around the hepatic hilar region. Result: We made artificial liver plasma exchange therapy several times waiting for liver transplantation. After liver transplantation, the dying patient began to recover who had gone throngh mycotic infection and rejecting. Conclusion: For this case, we think it is useful to the clinical diagnosis and treatment of patients who have liver failure caused by portal hypertension combining with portal ductopathy.
(8.0+极速模式)