Background: Intracranial schwannomas are common primary brain tumors, which typically originate from the trigeminal nerve or the vestibular nerve. Schwannoma arising in the sellar region is an extremely rare clinical entity, which mimics pituitary adenoma and poses a great diagnostic challenge. Case description: Herein, we describe two cases of sellar schwannoma. In the first case, a sellar lesion was incidentally found in a 51-year-old asymptomatic female; surgical resection via the Trans-sphenoidal approach was performed. The postoperative course was uneventful. The second patient was a 50-year-old man who presented with a history of headache for 4 months. Magnetic resonance imaging showed a sellar lesion extending into the right cavernous sinus region. Surgical resection was performed via the right frontotemporal approach. Additionally, we reviewed the published literature and identified a total of 30 cases of sellar schwannoma. A brief analysis and a summary of the individual clinical manifestations, radiological characteristics, pathological findings, treatment details, and outcomes of these cases are presented. Conclusion: Intrasellar schwannoma is an exceedingly rare entity. Surgical resection is an effective treatment option. Preoperative differential diagnosis is typically challenging. Definitive diagnosis depends on histopathological and immunohistochemical evidence.
[1]Jilin Univ, Hosp 1, Dept Neurosurg, Changchun 130021, Jilin, Peoples R China
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