This study was to investigate the antimicrobial resistance of coagulase-negative Staphylococci isolated in 8 consecutive years in the First Bethune Hospital. Disk diffusion test was used to study the antimicrobial resistance. The data were analyzed by WHONET 5 software according to Clinical and Laboratory Standards Institute (CLSI). Most of 2484 strains of coagulase-negative Staphylococci were collected from blood 925 (37.2%), secretions 652 (26.2%) and urine 323 (13.0%) during the past 8 years. The rates of methicillin-resistant coagulase-negative Staphylococci (MRCNS) were between 79.4 and 81.5 during the past 8 years, respectively. In recent 8 years, the antimicrobial resistance of coagulase-negative Staphylococci had increased. Monitoring the antimicrobial resistance to coagulase-negatives Staphylococci should be strengthened. The change of the antimicrobial resistance should be investigated in order to direct rational drug usage in the clinic and prevent bacterial strain of drug resistance from being transmitted. (C) 2012 Published by Elsevier B. V. Selection and/or peer review under responsibility of ICMPBE International Committee.
[1]Jilin Univ, Bethune Hosp 1, Changchun 130023, Peoples R China.
(8.0+极速模式)