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Effects of antigliomatin from the scorpion venom of Buthus martensii Karsch on chloride channels on C6 glioma cells 期刊论文

编号：

a95b085a-e49d-40c7-9cbd-b447d88bcf7f
作者：

Wang, Zan(王赞)#^[1]Li, Mingxian(李明娴)#^[2]Meng, Hongmei(孟红梅)^[1]Huang, Min^[3];Lin, Weihong(林卫红)*^[1]Cui, Li(崔俐)*^[1]Wang, Shao^[3];
语种：

英文
期刊：

NEURAL REGENERATION RESEARCH ISSN：1673-5374 2011 年 6 卷 18 期 (1365 - 1369) ; JUN
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关键词：

antigliomatin C6 glioma cells chloride channels osmotic pressure whole-cell patch-clamp recording
摘要：

Using whole-cell patch-clamp recordings, the effects of antigliomatin were observed on chloride channels on C6 glioma cells cultured in vitro. Antigliomatin was extracted from the venom of the scorpion Buthus martensii Karsch. Chloride channels are closed under normal osmotic pressure. When osmotic pressure was reduced to 120, 110 and 100 mV, the cell volume enlarged, chloride channels opened, and the chloride channel current increased. Three minutes after antigliomatin treatment, the chloride channel current decreased in a dose-dependent manner. These results show that antigliomatin extracted from the venom of the scorpion Buthus martensii Karsch diminishes chloride channel currents on C6 glioma cells.
推荐引用方式
GB/T 7714：

Wang Zan,Li Mingxian,Meng Hongmei, et al. Effects of antigliomatin from the scorpion venom of Buthus martensii Karsch on chloride channels on C6 glioma cells [J].NEURAL REGENERATION RESEARCH,2011,6(18):1365-1369.
APA：

Wang Zan,Li Mingxian,Meng Hongmei,Huang Min,&Wang Shao.(2011).Effects of antigliomatin from the scorpion venom of Buthus martensii Karsch on chloride channels on C6 glioma cells .NEURAL REGENERATION RESEARCH,6(18):1365-1369.
MLA：

Wang Zan, et al. "Effects of antigliomatin from the scorpion venom of Buthus martensii Karsch on chloride channels on C6 glioma cells" .NEURAL REGENERATION RESEARCH 6,18(2011):1365-1369.
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