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Study on the change of Caspase-3 and protective effect of EGb in hypoxic ischemic brain damage of neonatal rats 期刊论文

编号：

ef51b11d-879e-4de7-86c9-c93c002ae2bb
作者：

Li, Yumei(李玉梅)#;Yan, Chaoying;Hou, Shanshan;Dai, Chunlai(戴春来)
作者单位：

(1) Department of Neonatology, First Hospital of Jilin University, Changchun, China (2) First Hospital of Jilin University, Changchun, China
语种：

英文
会议名称：

Proceedings 2011 International Conference on Human Health and Biomedical Engineering, HHBE 2011
会议地点：

Jilin, China
收录：
摘要：

To assess the expression of Caspase-3 protein in brain after hypoxic ischemic (HI) and investigate the protective effect of extract of ginkgo biloba (EGb) on hypoxic ischemic brain damage (HIBD) in neonatal rats. The HIBD animal models were made by ligating the uterine arteries of pregnant rat. EGb was injected into the HIBD models. The expression of Caspase-3 protein in brain after HI was observed. As a Result Caspase-3 protein expression was elevated after HI and reperfusion while apoptosis of cerebral cells were also elevated. The study showed that the Caspase-3 protein was decreased with the treatment of EGb after HI. EGb decreased the apoptosis of cerebral cells. This indicates Caspase-3 may be function as a cell death effector protein. EGb has protective effect on HIBD which minimize the expression of Caspase-3 protein. © 2011 IEEE.
推荐引用方式
GB/T 7714：

Li Yumei (1),Yan Chaoying (1),Hou Shanshan (1), et al. Study on the change of Caspase-3 and protective effect of EGb in hypoxic ischemic brain damage of neonatal rats [J].Proceedings 2011 International Conference on Human Health and Biomedical Engineering, HHBE 2011,2011:385-387.
APA：

Li Yumei (1),Yan Chaoying (1),Hou Shanshan (1),Dai Chunlai (2).(2011).Study on the change of Caspase-3 and protective effect of EGb in hypoxic ischemic brain damage of neonatal rats .Proceedings 2011 International Conference on Human Health and Biomedical Engineering, HHBE 2011:385-387.
MLA：

Li Yumei (1), et al. "Study on the change of Caspase-3 and protective effect of EGb in hypoxic ischemic brain damage of neonatal rats" .Proceedings 2011 International Conference on Human Health and Biomedical Engineering, HHBE 2011(2011):385-387.
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